Screening for Disease
Contents
Page 1
Introduction
Learning Objectives
Page 2
The Utility of Screening
The Detectable Pre-Clinical Phase
When Screening Can Be Beneficial
Characteristics of a Good Screening Test
Sources of Unreliability (Inconsistency)
Page 3
Test Validity
Sensitivity
Specificity
Page 4
The Criterion of Positivity
ROC Curves
Page 5
Positive and Negative Predictive Value
Positive Predictive Value
Negative Predictive Value
Screening Validity Calculator
Page 6
The Yield of a Screening Program
Page 7
Adverse Effects of Screening
Over-Diagnosis
Page 8
Evaluating Screening Programs
Self-Selection Bias
Lead-Time Bias
Length Time Bias
Page 9
Screening for Down Syndrome (Optional)
Page 10
Other Resources
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