Analysis of a Cohort Study Using an Excel Spreadsheet

The video below (21 min.) will demonstrate how to analyze a large cohort study for which data has been stored in an Excel spreadsheet.

alternative accessible content

A Critical Thinking Exercise

Moderate Exercise or Just Take a Statin?

This exercise is based on the following two journal articles that focus on strategies to prevent cardiovascular disease. Links to the full articles are provided below.

  1. Manson et al.: A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in women. N. Engl. J. Med. 1999;341:650-8.
  2. Ridker PM, Danielson E, et al.: Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 2008; 359:2195-2207.

Compare and contrast the potential utility of each of these interventions as strategies to reduce cardiovascular disease in a population. In your discussion you should address issues of feasibility, cost, adherence, and risk versus benefit. Would you favor one intervention over the other? Why?